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Topotecan hydrochloride
CAS No. 119413-54-6
Topotecan hydrochloride ( Hycamtin; NSC 609669; SKF 104864A )
Catalog No. M10677 CAS No. 119413-54-6
Topotecan HCl (SKF 104864A; NSC 609669) is the first topoisomerase I-directed cytotoxic agent to enter clinical trials in the United States.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 27 | In Stock |
|
| 10MG | 42 | In Stock |
|
| 25MG | 66 | In Stock |
|
| 50MG | 98 | In Stock |
|
| 100MG | 132 | In Stock |
|
| 500MG | 327 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTopotecan hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionTopotecan HCl (SKF 104864A; NSC 609669) is the first topoisomerase I-directed cytotoxic agent to enter clinical trials in the United States.
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DescriptionTopotecan HCl (SKF 104864A; NSC 609669) is the first topoisomerase I-directed cytotoxic agent to enter clinical trials in the United States.
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SynonymsHycamtin; NSC 609669; SKF 104864A
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PathwayCell Cycle/DNA Damage
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TargetTopoisomerase
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RecptorTopo I (DU-145 Luc cells); Topo I (MCF-7 Luc cells)
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number119413-54-6
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Formula Weight457.92
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Molecular FormulaC23H24ClN3O5
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Purity>98%(HPLC)
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SolubilityWater: 92 mg/mL (200.91 mM); DMSO: 92 mg/mL (200.91 mM)
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SMILESCC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=C(C5=C4)CN(C)C)O)O.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Caceres G, et al. anticancer Drugs. 2003, 14(7), 569-574.
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