Topotecan hydrochloride

CAS No. 119413-54-6

Topotecan hydrochloride ( Hycamtin; NSC 609669; SKF 104864A )

Catalog No. M10677 CAS No. 119413-54-6

Topotecan HCl (SKF 104864A; NSC 609669) is the first topoisomerase I-directed cytotoxic agent to enter clinical trials in the United States.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 27 In Stock
10MG 42 In Stock
25MG 66 In Stock
50MG 98 In Stock
100MG 132 In Stock
500MG 327 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Topotecan hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Topotecan HCl (SKF 104864A; NSC 609669) is the first topoisomerase I-directed cytotoxic agent to enter clinical trials in the United States.
  • Description
    Topotecan HCl (SKF 104864A; NSC 609669) is the first topoisomerase I-directed cytotoxic agent to enter clinical trials in the United States.
  • Synonyms
    Hycamtin; NSC 609669; SKF 104864A
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Topoisomerase
  • Recptor
    Topo I (DU-145 Luc cells); Topo I (MCF-7 Luc cells)
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    119413-54-6
  • Formula Weight
    457.92
  • Molecular Formula
    C23H24ClN3O5
  • Purity
    >98%(HPLC)
  • Solubility
    Water: 92 mg/mL (200.91 mM); DMSO: 92 mg/mL (200.91 mM)
  • SMILES
    CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=C(C5=C4)CN(C)C)O)O.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Caceres G, et al. anticancer Drugs. 2003, 14(7), 569-574.
molnova catalog
related products
  • Nalidixic acid sodiu...

    A synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum.

  • Teniposide

    Teniposide(VM-26) is a semisynthetic derivative of podophyllotoxin and are increasingly used in Y medicine.

  • SW-044248

    SW-044248 is a novel selective inhibitor of Topoisomerase I; inhibits Top I differently from camptothecin.